Ever wondered how impenetrable skin might actually work? Barry Fitzgerald (of Delft University of Technology) contends that Colossus could form a graphene layer via a protein folding and protein self-assembly process.
 

One super-power that gains constant attention is that of impenetrability, a power possessed by superheroes like Luke Cage, Wonder Woman, Superman and Colossus. In a recent paper in Advances in Physiology Education, Barry W. Fitzgerald considers how Colossus’ skin might work.
 
Colossus is a member of the X-Men and has appeared in films such as X-Men: The Last StandX-Men: Days of Future PastDeadpool and Deadpool 2. Like the other X-Men, Colossus’ DNA contains the X-gene, which is behind his super-power. Colossus has the ability to create an “organic steel” layer on his skin that is impenetrable and protects his body.
 
“The key to Colossus’ power of impenetrability is a change in the structure of his skin,” says Fitzgerald. When Colossus changes to his “organic steel” form, this directly affects the epidermis and dermis in the skin, which can have serious physiological repercussions for Colossus. For instance, thermoregulation is an important process that keeps the core temperature at about 37°C. “When Colossus is in his steel form, his body’s ability to thermoregulate may be severely hampered,” says Fitzgerald. As a result, Colossus’ super-power could actually be fatal.
 
Fitzgerald contends that Colossus could form a graphene layer via a protein folding and protein self-assembly process. Fitzgerald outlines the key steps in the production of his proposed Colossus bio-graphene layer, and issues that may arise during its formation, such as changes to blood viscosity.
 
Fitzgerald says, “If Colossus’ impenetrable skin were composed of a bio-graphene protein lattice layer, a number of physiological problems could be addressed.” He then describes how a bio-graphene layer would allow Colossus to thermoregulate, retain electrolytes while battling villains, and ensure that Colossus can always see, even when covered by an impenetrable bio-graphene layer.”

 
The physiology of impenetrable skin: Colossus of the X-men
Source: Alerts
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